Review



um-uc-14  (CancerTools Org)


Bioz Verified Symbol CancerTools Org is a verified supplier
Bioz Manufacturer Symbol CancerTools Org manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 99
      Buy from Supplier

    Structured Review

    CancerTools Org um-uc-14
    Um Uc 14, supplied by CancerTools Org, used in various techniques. Bioz Stars score: 99/100, based on 189 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/umuc+14/UM-UC-14/custom%40160443%4041223749
    Average 99 stars, based on 189 article reviews
    um-uc-14 - by Bioz Stars, 2026-10
    99/100 stars

    Images

    Related Articles

    Derivative Assay:

    Article Title: Discovery of TBK1-associated oncogenic mechanisms in patients with upper tract urothelial carcinoma and preexisting end-stage renal disease
    Article Snippet: Micro-abstract: This study investigates oncogenic mechanisms in upper tract urothelial carcinoma (UTUC) patients with end-stage renal disease (ESRD), who face limited perioperative treatment options.. Using RNA sequencing and gene set enrichment analysis on UTUC tumor samples, we identified TBK1associated gene sets activated in ESRD-UTUC patients.. Withaferin A, an IKK inhibitor, reduced UTUC cell viability and migration, suggesting therapeutic potential.

    In Vitro:

    Article Title: Discovery of TBK1-associated oncogenic mechanisms in patients with upper tract urothelial carcinoma and preexisting end-stage renal disease
    Article Snippet: Micro-abstract: This study investigates oncogenic mechanisms in upper tract urothelial carcinoma (UTUC) patients with end-stage renal disease (ESRD), who face limited perioperative treatment options.. Using RNA sequencing and gene set enrichment analysis on UTUC tumor samples, we identified TBK1associated gene sets activated in ESRD-UTUC patients.. Withaferin A, an IKK inhibitor, reduced UTUC cell viability and migration, suggesting therapeutic potential.



    Similar Products

    um-uc-14  (CancerTools Org)
    99
    CancerTools Org um-uc-14
    Um Uc 14, supplied by CancerTools Org, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/umuc+14/UM-UC-14/custom%40160443%4041223749
    Average 99 stars, based on 1 article reviews
    um-uc-14 - by Bioz Stars, 2026-10
    99/100 stars
    		  Buy from Supplier
    umuc 14  (CancerTools Org)
    99
    CancerTools Org umuc 14
    Umuc 14, supplied by CancerTools Org, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/umuc+14/UM-UC-14+(Human+transitional+cell+carcinoma+of+the+renal+pelvis)+cell+line/10__1016_slash_j__clgc__2025__102420-96-6-7
    Average 99 stars, based on 1 article reviews
    umuc 14 - by Bioz Stars, 2026-10
    99/100 stars
    		  Buy from Supplier
    umuc-14 cells  (Korean Cell Line Bank)
    90
    Korean Cell Line Bank umuc-14 cells
    FGFR1 expression is correlated with EMT features and PTX resistance in UC cell lines. ( A ) T24, J82, <t>RT4,</t> UMUC-14, HTB5, and HTB9 cells were evaluated basal expression of FGFRs and EMT-associated proteins by Western blotting; β-actin served as a loading control. ( B ) Colony formation assay. T24, J82, RT4, and UMUC-14 cells were grown for 7 days, then stained with Coomassie Brilliant Blue and counted. ( C ) T24, J82, RT4, and UMUC-14 cells were treated with 0, 1, 10, 100, and 1000 nM PTX for 3 days. IC 50 values were calculated using CalcuSyn (BioSoft, Ferguson, MO, USA). Data represent the mean ± standard deviation of five replicates. ( D ) Cell cycle analysis by propidium iodide staining and flow cytometry. A total of 1 × 10 6 cells were seeded in 60-mm plates and treated with 0, 5, and 10 nM PTX for 48 h. Data are presented as histograms (blue, G0/G1 phase; green, S phase, and red, G2/M phase). ( E ) Cyclin B , p21 , p27 , γ-H2AX , caspase-3 , and PARP expression in T24, J82, UMUC-14, and RT4 cells, as determined by Western blotting; β-actin served as the loading control.
    Umuc 14 Cells, supplied by Korean Cell Line Bank, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/umuc+14/umuc+14+cells/pmc06214101-141-1-12
    Average 90 stars, based on 1 article reviews
    umuc-14 cells - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    FGFR1 expression is correlated with EMT features and PTX resistance in UC cell lines. ( A ) T24, J82, RT4, UMUC-14, HTB5, and HTB9 cells were evaluated basal expression of FGFRs and EMT-associated proteins by Western blotting; β-actin served as a loading control. ( B ) Colony formation assay. T24, J82, RT4, and UMUC-14 cells were grown for 7 days, then stained with Coomassie Brilliant Blue and counted. ( C ) T24, J82, RT4, and UMUC-14 cells were treated with 0, 1, 10, 100, and 1000 nM PTX for 3 days. IC 50 values were calculated using CalcuSyn (BioSoft, Ferguson, MO, USA). Data represent the mean ± standard deviation of five replicates. ( D ) Cell cycle analysis by propidium iodide staining and flow cytometry. A total of 1 × 10 6 cells were seeded in 60-mm plates and treated with 0, 5, and 10 nM PTX for 48 h. Data are presented as histograms (blue, G0/G1 phase; green, S phase, and red, G2/M phase). ( E ) Cyclin B , p21 , p27 , γ-H2AX , caspase-3 , and PARP expression in T24, J82, UMUC-14, and RT4 cells, as determined by Western blotting; β-actin served as the loading control.

    Journal: International Journal of Molecular Sciences

    Article Title: BGJ398, A Pan-FGFR Inhibitor, Overcomes Paclitaxel Resistance in Urothelial Carcinoma with FGFR1 Overexpression

    doi: 10.3390/ijms19103164

    Figure Lengend Snippet: FGFR1 expression is correlated with EMT features and PTX resistance in UC cell lines. ( A ) T24, J82, RT4, UMUC-14, HTB5, and HTB9 cells were evaluated basal expression of FGFRs and EMT-associated proteins by Western blotting; β-actin served as a loading control. ( B ) Colony formation assay. T24, J82, RT4, and UMUC-14 cells were grown for 7 days, then stained with Coomassie Brilliant Blue and counted. ( C ) T24, J82, RT4, and UMUC-14 cells were treated with 0, 1, 10, 100, and 1000 nM PTX for 3 days. IC 50 values were calculated using CalcuSyn (BioSoft, Ferguson, MO, USA). Data represent the mean ± standard deviation of five replicates. ( D ) Cell cycle analysis by propidium iodide staining and flow cytometry. A total of 1 × 10 6 cells were seeded in 60-mm plates and treated with 0, 5, and 10 nM PTX for 48 h. Data are presented as histograms (blue, G0/G1 phase; green, S phase, and red, G2/M phase). ( E ) Cyclin B , p21 , p27 , γ-H2AX , caspase-3 , and PARP expression in T24, J82, UMUC-14, and RT4 cells, as determined by Western blotting; β-actin served as the loading control.

    Article Snippet: UMUC-14, RT4, T24, J82, HTB5, and HTB9 cells were purchased from the Korean Cell Line Bank (Seoul, Korea).

    Techniques: Expressing, Western Blot, Control, Colony Assay, Staining, Standard Deviation, Cell Cycle Assay, Flow Cytometry

    FGFR inhibition enhances PTX-induced cell cycle arrest in mesenchymal-type UC cell lines. ( A ) T24, J82, RT4, and UMUC-14 cells were treated with 0, 0.1, 1, and 10 μM BJG398 for 3 days. IC 50 values were calculated using CalcuSyn (BioSoft, Ferguson, MO, USA). Data represent mean ± standard deviation of five replicates. ( B ) Cells were exposed to increasing concentrations of PTX and BGJ398 combinations at a fixed ratio. Viable cells were assayed and CI was calculated using CalcuSyn software. Lines above each bar represent CI for that dose combination ( n = 3). ( C ) Cell cycle distribution and apoptosis were analyzed by propidium iodide staining and flow cytometry. A total of 1 × 10 6 cells were seeded in a 60-mm plate and treated with indicated concentrations of PTX and BGJ398 for 48 h ( n = 3). ( D ) Quantification of cell cycle distribution of T24, J82, RT4, and UMUC-14 cells.

    Journal: International Journal of Molecular Sciences

    Article Title: BGJ398, A Pan-FGFR Inhibitor, Overcomes Paclitaxel Resistance in Urothelial Carcinoma with FGFR1 Overexpression

    doi: 10.3390/ijms19103164

    Figure Lengend Snippet: FGFR inhibition enhances PTX-induced cell cycle arrest in mesenchymal-type UC cell lines. ( A ) T24, J82, RT4, and UMUC-14 cells were treated with 0, 0.1, 1, and 10 μM BJG398 for 3 days. IC 50 values were calculated using CalcuSyn (BioSoft, Ferguson, MO, USA). Data represent mean ± standard deviation of five replicates. ( B ) Cells were exposed to increasing concentrations of PTX and BGJ398 combinations at a fixed ratio. Viable cells were assayed and CI was calculated using CalcuSyn software. Lines above each bar represent CI for that dose combination ( n = 3). ( C ) Cell cycle distribution and apoptosis were analyzed by propidium iodide staining and flow cytometry. A total of 1 × 10 6 cells were seeded in a 60-mm plate and treated with indicated concentrations of PTX and BGJ398 for 48 h ( n = 3). ( D ) Quantification of cell cycle distribution of T24, J82, RT4, and UMUC-14 cells.

    Article Snippet: UMUC-14, RT4, T24, J82, HTB5, and HTB9 cells were purchased from the Korean Cell Line Bank (Seoul, Korea).

    Techniques: Inhibition, Standard Deviation, Software, Staining, Flow Cytometry